ALKBH2, 1-261aa, Human, His tag, E.coli from IBL- America

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Supplier Page from
IBL- America for
ALKBH2, 1-261aa, Human, His tag, E.coli

Description

Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, also known ALKBH2, belongs to the ALKB family. Expressed in heart, colon, liver, testis, ovary, prostate and small intestine, ALKBH2 uses iron as a cofactor and functions as a dioxygenase that catalyzes the repair of alkylated DNA and RNA containing 1- methyladenine and 3-meth-ylcytosine. ALKBH2 is functionally activated by ascorbate and requires oxygen and α- ketoglutarate for enzymatic activity